The church of San Isidro el Real, also known as the church of the Colegiata or Collegium of San Isidro, is a Baroque church in central Madrid, central Spain. It is named after and holds the remains of the patron saint of Madrid, Isidore the Laborer and his wife Santa Maria de la Cabeza.
The Collegium of San Isidro, also known as the Colegio Imperial de Madrid, was designed in 1620 by the architect Pedro Sánchez, and posthumously completed by Francisco Bautista and Melchor de Bueras, in 1664. Construction of a series of buildings for the Jesuit order had been endowed by Maria of Austria, daughter of King Charles I of Spain. The parish church located at the site was demolished.
In 1769, the remains of the patron saint were transferred here from the church of San Andrés, Madrid. Until the completion of the catedral of the Almudena in 1993, this served as the cathedral of Madrid.
During the civil war in 1936, a fire caused extensive damage. Since 1978, it is the home of a new order, the Brotherhood of Nuestro Padre Jesús del Gran Poder y María Santísima de la Esperanza Macarena.
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